Neural Information Processing Systems http://nips.cc/

Estimation of differences in conditional independence graphs (CIGs) of two time series Gaussian graphical models (TSGGMs) is investigated where the two TSGGMs are known to have similar structure. The TSGGM structure is encoded in the inverse power spectral density (IPSD) of the time series. In several existing works, one is interested in estimating the difference in two precision matrices to characterize underlying changes in conditional dependencies of two sets of data consisting of independent and identically distributed (i.i.d.) observations. In this paper we consider estimation of the difference in two IPSDs to characterize the underlying changes in conditional dependencies of two sets of time-dependent data. Our approach accounts for data time dependencies unlike past work. We analyze a penalized D-trace loss function approach in the frequency domain for differential graph learning, using Wirtinger calculus. We consider both convex (group lasso) and non-convex (log-sum and SCAD group penalties) penalty/regularization functions. An alternating direction method of multipliers (ADMM) algorithm is presented to optimize the objective function. We establish sufficient conditions in a high-dimensional setting for consistency (convergence of the inverse power spectral density to true value in the Frobenius norm) and graph recovery. Both synthetic and real data examples are presented in support of the proposed approaches. In synthetic data examples, our log-sum-penalized differential time-series graph estimator significantly outperformed our lasso based differential time-series graph estimator which, in turn, significantly outperformed an existing lasso-penalized i.i.d. modeling approach, with $F_1$ score as the performance metric.

In many cases of network analysis, it is more attractive to study how a network varies under different conditions than an individual static network. We propose a novel graphical model, namely Latent Differential Graph Model, where the networks under two different conditions are represented by two semiparametric elliptical distributions respectively, and the variation of these two networks ( i.e.,

We consider the problem of estimating the difference between two functional undirected graphical models with shared structures. In many applications, data are naturally regarded as high-dimensional random function vectors rather than multivariate scalars. For example, electroencephalography (EEG) data are more appropriately treated as functions of time.

We consider the problem of estimating differences in two multi-attribute Gaussian graphical models (GGMs) which are known to have similar structure, using a penalized D-trace loss function with non-convex penalties. The GGM structure is encoded in its precision (inverse covariance) matrix. Existing methods for multi-attribute differential graph estimation are based on a group lasso penalized loss function. In this paper, we consider a penalized D-trace loss function with non-convex (log-sum and smoothly clipped absolute deviation (SCAD)) penalties. Two proximal gradient descent methods are presented to optimize the objective function. Theoretical analysis establishing sufficient conditions for consistency in support recovery, convexity and estimation in high-dimensional settings is provided. We illustrate our approaches with numerical examples based on synthetic and real data.

In many cases of network analysis, it is more attractive to study how a network varies under different conditions than an individual static network. We propose a novel graphical model, namely Latent Differential Graph Model, where the networks under two different conditions are represented by two semiparametric elliptical distributions respectively, and the variation of these two networks (i.e., differential graph) is characterized by the difference between their latent precision matrices. We propose an estimator for the differential graph based on quasi likelihood maximization with nonconvex regularization. We show that our estimator attains a faster statistical rate in parameter estimation than the state-of-the-art methods, and enjoys the oracle property under mild conditions. Thorough experiments on both synthetic and real world data support our theory.

We consider the problem of estimating differences in two Gaussian graphical models (GGMs) which are known to have similar structure. The GGM structure is encoded in its precision (inverse covariance) matrix. In many applications one is interested in estimating the difference in two precision matrices to characterize underlying changes in conditional dependencies of two sets of data. Existing methods for differential graph estimation are based on single-attribute (SA) models where one associates a scalar random variable with each node. In multi-attribute (MA) graphical models, each node represents a random vector. In this paper, we analyze a group lasso penalized D-trace loss function approach for differential graph learning from multi-attribute data. An alternating direction method of multipliers (ADMM) algorithm is presented to optimize the objective function. Theoretical analysis establishing consistency in support recovery and estimation in high-dimensional settings is provided. Numerical results based on synthetic as well as real data are presented.

We consider the problem of estimating the difference between two functional undirected graphical models with shared structures. In many applications, data are naturally regarded as high-dimensional random function vectors rather than multivariate scalars. For example, electroencephalography (EEG) data are more appropriately treated as functions of time. In these problems, not only can the number of functions measured per sample be large, but each function is itself an infinite dimensional object, making estimation of model parameters challenging. In practice, curves are usually discretely observed, which makes graph structure recovery even more challenging. We formally characterize when two functional graphical models are comparable and propose a method that directly estimates the functional differential graph, which we term FuDGE. FuDGE avoids separate estimation of each graph, which allows for estimation in problems where individual graphs are dense, but their difference is sparse. We show that FuDGE consistently estimates the functional differential graph in a high-dimensional setting for both discretely observed and fully observed function paths. We illustrate finite sample properties of our method through simulation studies. In order to demonstrate the benefits of our method, we propose Joint Functional Graphical Lasso as a competitor, which is a generalization of the Joint Graphical Lasso. Finally, we apply our method to EEG data to uncover differences in functional brain connectivity between alcoholics and control subjects.